Its significance as to the natural history aside, the Botanical Garden of Pisa (Orto Botanico di Pisa) is valuable for the city given it is the oldest University Botanical Garden in Europe. Founded upon the order to Cosimo I de Medici in 1544, the Botanical Garden of Pisa used to be located on the site different from the one on which is lies today, filling a 3 hectare surface. Yet, despite the loss of a certain specimens which, one may believe, were recovered soon after, the garden thrived in the centuries to come given the patronage of the Medici family. This establishment pertains to the University of Pisa, and it hosts the Botanical Institute, being split into areas comprising open air plants from various climatic regions and several greenhouses.

Botanical Garden of Pisa
Via Luca Ghini 5, Pisa, Italy